Anomalies et malformations congénitales

Congenital anomalies and malformations

Congenital anomalies and malformations are structural or functional defects in a part of the body that are present at birth. Santé publique France conducts epidemiological surveillance of these conditions.

Our Mission

  • To coordinate and support the work of registries in the area of monitoring and evaluating public health initiatives

  • Analyze longitudinal trends in the incidence of congenital anomalies and regional disparities

  • Assess the suitability of using medical-administrative databases to identify valid information for the epidemiological surveillance of congenital anomalies

  • Inform the general public by making available epidemiological data accessible and visible

The Disease

What is a congenital anomaly?

Congenital anomalies are structural defects affecting one or more organs. They result either from an abnormality that disrupted the normal developmental process of the embryo or fetus, or from a genetic cause. Genetic information, contained in the nucleus of every cel...

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Our Work

Epidemiological Surveillance of Congenital Anomalies

Epidemiological surveillance of congenital anomalies arose largely in response to the increase in cases of limb abnormalities caused by thalidomide, a drug widely prescribed to pregnant women between the 1950s and 1960s. Surveillance systems wer...

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Data

An increase in the number of births with at least one congenital anomaly 

In 2022, the prevalence of cases with at least one major congenital anomaly (according to the EUROCAT classification) stood at 342.0 cases per 10,000 total births, or 1 case per 29 births. Trend analysis reveals a significan...

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Publications

Find here the latest scientific publications related to the studies and research conducted by Santé Publique France;

2 publications