Key Points

• Syndromic and virological indicators remained at low levels, although they were increasing in the city and, to a lesser extent, in the hospital.

• Increased circulation of SARS-CoV-2 was observed through wastewater surveillance.

• The detection of COVID-19 clusters in long-term care facilities had been increasing since Week 20.

• Waves of COVID-19 have already been observed in the spring and summer since the start of the pandemic. They are not systematically linked to the emergence of a new variant, but may be related to individual immunity and population behaviors that can facilitate transmission.

• These trends, and in particular the increase in SARS-CoV-2 detection in laboratory samples and wastewater, point to a resurgence of viral circulation, the impact of which on the healthcare system should be monitored in the coming weeks.