COVID-19 Epidemiological Update for January 5, 2023 - Epidemic monitoring indicators are declining but remain at high levels
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Published weekly, the epidemiological update on COVID-19 surveillance provides a detailed analysis of the indicators established by Santé publique France and its network of partners to track the progression of the epidemic and inform public policy decisions.
Incidence rates are declining, amid a sharp drop in testing rates
In Week 52 (December 26, 2022, to January 1, 2023), virological indicators of SARS-CoV-2 circulation were declining nationwide and across the entire metropolitan area. The incidence rate fell sharply (-50%) to 210 cases per 100,000 inhabitants. It fell below 50 per 100,000 among those under 20 and remained highest among older age groups. This decline in the incidence rate occurred against a backdrop of a significant decrease in the testing rate (1,110 per 100,000, -44%), particularly among those under 60. The positivity rate continued to decline (18.9%, -2.5 percentage points), though there was a slight increase among those under 20, where it remained the lowest. Indicators of healthcare utilization for suspected COVID-19 at SOS Médecins and emergency departments followed the same trend.
New hospital admissions remain high
In week 52, the number of new hospitalizations—the figure for which will be finalized in the next Epidemiological Update—decreased for the second consecutive week (4,999, -40%—unfinalized data). Consolidated data from the previous week, meanwhile, showed a decrease in new admissions (8,289, -16%) in week 51 (-14% in critical care).
Focus on Genomic Surveillance in 2023
Genomic surveillance, in France and around the world, aims to identify emerging SARS-CoV-2 variants early on, based on the sequencing of a sample of positive specimens, which is reassessed weekly depending on the number of cases. Surveillance needs are also evolving in light of other factors, such as the introduction of new variants of concern or the emergence of resistance to curative treatments.
The EMERGEN consortium’s surveillance and research activities will continue in 2023 under the coordination of Santé publique France and ANRS|MIE. Since January 1, 2023, sequencing activities have been centralized at the National Reference Center (CNR) for Respiratory Infection Viruses (Hospices Civils de Lyon, Institut Pasteur), in collaboration with medical biology laboratories that collect samples and with the support of hospital laboratories in the ANRS|MIE network. Weekly Flash surveys are also continuing, and all sequences generated are centralized on the EMERGEN-DB platform; they are also published on Gisaid for international sharing. Their results are reported and made available on the InfoCovidFrance dashboard and in the Weekly Epidemiological Report.
Sequencing capacity within the EMERGEN consortium, in its current configuration, is approximately 10,000 sequences per week. Currently, the CNR’s capacity alone (4,000 sequences per week) is sufficient to meet the needs for genomic surveillance of SARS-CoV-2 variants (weekly Flash surveys and airport surveillance), in accordance with European recommendations.
Omicron is circulating almost exclusively in France, and its BA.5 sublineage remains ubiquitous
In mainland France, BA.5 (all sublineages combined) accounted for 93% of interpretable sequences in the Flash S50 survey (12/12, based on 1,704 interpretable sequences). Among the BA.5 sublineages, detection of the BQ.1.1 sublineage (including its sublineages) continued to increase at a steady rate, accounting for 70% of interpretable sequences during the Flash S50 survey (vs. 67% for Flash S49). For more information: Risk analysis related to emerging SARS-CoV-2 variants (12/14/2022)
Winter viruses still circulating: adherence to combined measures must continue
As of January 2, 2023, 16.3% of those aged 60–79 and 19.6% of those aged 80 and older had received a booster tailored to the Omicron variant (21.8% and 23.2% respectively among those eligible)1. Furthermore, 32.7% of those aged 60–79 were considered protected by vaccination (last dose administered within the past 6 months), as were 21.0% of those aged 80 and older (last dose administered within the past 3 months)2.
Vaccination coverage among healthcare professionals for the complete primary vaccination series, the first booster dose, and the booster adapted to the Omicron variant is estimated at 95.6%, 86.2%, and 10.1%, respectively, among those working in nursing homes, 97.7%, 88.8%, and 11.4% among private practitioners, and 96.6%, 88.3%, and 11.6% among those working in healthcare facilities³. The fall vaccination campaign, including the booster dose adapted to the Omicron variant, began on October 3, 2022.
In this context, strengthening COVID-19 vaccination efforts—particularly through a booster dose with a bivalent vaccine (against the original strain and the Omicron variant) for eligible individuals who have received their initial vaccination (starting 3 or 6 months after the last dose, according to current recommendations)—is essential.
Furthermore, given the high circulation of the flu in the country, it is strongly recommended that individuals at risk of developing severe flu get vaccinated against seasonal flu as soon as possible. Flu and COVID-19 vaccinations can be administered on the same day.
Adherence to preventive measures, including mask-wearing (in the presence of vulnerable individuals, or in crowded indoor spaces such as public transportation), remains necessary and must be emphasized to also protect the healthcare system. Compliance with other recommended measures remains essential: self-isolation in the event of a positive test and/or symptoms, handwashing, and ventilation of enclosed spaces.
As the bronchiolitis outbreak remains at high levels, parents of infants and young children, as well as those around them, are also advised to adopt preventive measures to limit the transmission of the virus that causes bronchiolitis.
For more information on COVID-19, surveillance systems, and vaccination, consult the Santé Publique France report and the Vaccination Info Service website. For more information on regional data, consult the regional epidemiological reports. Find all data freely available on Géodes.
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5 January 2023
COVID-19: Epidemiological Update for January 5, 2023
[1] Individuals who have received a booster dose tailored to Omicron variants are those who have completed their primary vaccination series and have received a booster dose with a bivalent vaccine (original Pfizer/Omicron BA.5 or original Moderna/Omicron BA.1), regardless of whether they previously received one, several, or no booster doses. This is recommended 3 months after the last vaccine dose for those aged 80 and older, and 6 months for those aged 60–79 and others at risk of severe forms of COVID-19. To allow eligible individuals time to receive their shot, eligibility is determined one month after the last injection (4 months for those aged 80 and older and 7 months for those aged 60–79).
[2] All vaccines combined. These proportions do not account for SARS-CoV-2 infections that may have occurred during this period.
[3] Vaccination coverage is estimated for healthcare professionals working in nursing homes, healthcare facilities, and private practice, identified through the CNAM’s September 2021 matching of the RPPS (Shared Directory of Healthcare Professionals) and Adeli (Automation of Lists) registries with the Covid Vaccine database. Only doctors, pharmacists, midwives, physical therapists, dentists, and nurses are identified in these registries.
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