Key points: - Between 2001 and 2003, 4 cases of indigenous malaria in mainland France were reported through mandatory reporting (3 post-transplant and 1 post-transfusion). - Five other cases of indigenous malaria were reported: 3 cases of maternal-fetal malaria, 1 case following accidental exposure to blood, and 1 post-transplant case. - Malaria remains endemic in French Guiana and Mayotte. - In the French West Indies and Réunion, all cases reported from 2001 to 2003 were imported. (R.A.)