Key Points

• Typhoid Fever

  • 231 cases of typhoid fever reported in Mayotte between 2019 and 2022 (annual incidence rate of 18 cases per 100,000 inhabitants)

  • Sharp increase in the reporting rate in 2022 (41 cases per 100,000 inhabitants) following a decline observed during the COVID-19 years (13.9 per 100,000 inhabitants in 2020 and 5 per 100,000 inhabitants in 2021)

  • The municipalities of Koungou and Dzaoudzi account for 70% of the cases reported in 2022

• Hepatitis A

  • A total of 290 cases of hepatitis A reported in Mayotte from 2019 to 2022 (an average of 73 cases per year)

  • Annual reporting rate has been declining since 2020 10.4 cases per 100,000 inhabitants in 2022 but remains the highest nationally

  • The municipalities in the north and center of the island are the most affected

• Diphtheria

  • Increase in the number of reported diphtheria cases in recent years: 29 cases between 2019 and 2022, nearly half of which (14 cases) occurred in 2022

  • Three unvaccinated infants under one year of age died between 2019 and 2022 (including two with toxigenic diphtheria)

  • Risk of resurgence due to insufficient vaccination coverage among children and adults