Key points: - In 2003, 10,472 human Salmonella strains and 382 clusters of salmonellosis cases were recorded by the CNR-Salm; - a 16.9% decrease in Salmonella isolates of human origin between 2001 and 2003; - the Enteritidis and Typhimurium serotypes remain the two main serotypes, accounting for 39.6% and 30.8% of isolates in 2003, respectively; - Overall stability in antibiotic resistance among the 10 serotypes studied, but detection of a few strains resistant to third-generation cephalosporins and ciprofloxacin. (R.A.)