Key Points

• In 2023, the annual incidence of pediatric HUS was lower than in 2022 (a year marked by a particularly high incidence linked to the occurrence of several outbreaks). It was once again comparable to the incidence rates observed between 2017 and 2021.

• Variations in regional incidence rates are observed each year. A study by Santé publique France published in 2023 demonstrated geographic disparities in the risk of sporadic pediatric HUS (not linked to an outbreak).

• In 2023, serogroup O26 remained the most prevalent.