The purpose of this report was to analyze vaccination data (vaccine types and dates of administration) collected during health screenings conducted in the middle section of preschool classes by the services of the former Corse-du-Sud Departmental Council, whose responsibilities have since been assumed by the Collectivité de Corse. The vaccine types analyzed were as follows: diphtheria-tetanus-polio (DTP), pertussis, Haemophilus influenzae type b (Hib), hepatitis B virus (HBV), pneumococcus, meningococcal C, and measles-mumps-rubella (MMR). The purpose of this study was to provide a better understanding of departmental vaccination coverage (VC) and its trends over the past few years. Vaccination coverage rates at 24 months were also compared with data from the 24-month health certificates (CS24). Finally, the age distribution at the time of the various vaccinations, compared with the recommended ages, was estimated. This analysis showed that the recommended 95% vaccination coverage targets, aimed at preventing the outbreak of epidemics, were not met, particularly for the pneumococcal vaccine (3 doses) and the MMR vaccine (1 dose), although coverage for these vaccines exceeded 90%. With a vaccination coverage of 50%, the CV for the meningococcal C vaccine was the lowest among the valences studied. Vaccine coverage rates were stable or increasing. In this study, a comparison between the vaccine coverage rates derived from the database analysis and those derived from the CS24 surveys showed that the latter were consistently higher, with the differences appearing to be all the greater the lower the vaccine coverage rate. Given the decline in CS24 data reporting in recent years, these results raise questions about the representativeness of the CS24 data. Finally, even though a slight deviation from the recommended dosing schedule does not necessarily have a significant impact on immunization, the analysis of adherence to the various schedules revealed a number of injections administered later than recommended in the vaccination calendar—and, in some cases, earlier as well. The next steps for this study include several points. First, at the local level, analyzing the database at the sub-departmental level could help identify potential areas with lower vaccination coverage so that targeted interventions can be implemented. Furthermore, to confirm the differences in vaccination coverage between this database and the CS24 reports, additional analyses should be considered. These should make it possible to investigate the causes of the discrepancies and, in particular, the issue of the representativeness of the CS24 reports, following the decline in data reporting. Finally, taking into account not only vaccination coverage in terms of doses but also adherence to the various vaccination schedules will most certainly be a key consideration for awareness-raising initiatives targeting physicians (understanding the effects of delays, ensuring vaccination coverage aligns with the schedules).