On Sunday, February 28, 2010, Storm Xynthia struck France, causing coastal flooding in the departments of Vendée and Charente-Maritime. Following this disaster, the Pays de la Loire Interregional Epidemiology Unit assessed the adequacy of the patient care system after Storm Xynthia based on: 1) a descriptive study of the activity of the Medical-Psychological Emergency Units (CUMP); 2) a surveillance system tracking storm-related consultations within a network of healthcare professionals in southern Vendée between June and December 2010; 3) interviews with network stakeholders conducted during September 2010. The CUMPs remained active for two and a half months following the disaster. They provided care to nearly 900 people. The monitoring system recorded 51 cases; 59% of patients were 65 years of age or older, and 90% had experienced trauma, half of which was deemed traumatic (evacuation, loss of a loved one). Three-quarters of patients exhibited symptoms of anxiety or depression, and 22% exhibited at least two signs of post-traumatic stress. Interviews with stakeholders confirmed limited storm-related activity. Overall, following the intervention by the CUMPs, the storm’s impact on the healthcare system in southern Vendée was moderate. However, the long-term psychological impact remains to be assessed through a population-based epidemiological study. This study highlighted the need for epidemiological data collection tools adapted to disaster contexts. (R.A)